• Rescue mechanism borrowed from plants
• Working with inflammation
• Key nesem extracts are shown to be anti-fungal in plants.
• Healthy Aging
• Healthy living

“A natural rescue mechanism borrowed from plants”

Salvestrol® are a class of natural compounds derived from fruits, herbs, and vegetables. These compounds are not naturally produced by the body and must be obtained through the diet.

Salvestrol® is a blend of key extracts form our everyday foods, which are now found in very low levels due to cropping and spraying, that help support our bodies, a protective and healthy support, for wellbeing and aging well.

These key extracts or nesems have been shown in plants to have anti-fungal and anti-inflammatory properties as well as regulating normal cell function.

Salvestrols work inside cells that have failed to behave like normal cells. Normal healthy cells stop dividing at the end of a natural life cycle and die, Salvestrols are used as part of the body’s natural cell cycle regulation. Research has shown that the CYP1B1 enzyme appears in unhealthy/damaged cells and is not detectable in healthy cells. The mechanism of Salvestrols is that they are converted by the CYP1B1 enzyme present in unhealthy cells into toxic metabolites which cause regulation of the cell cycle. As the CYP1B1 enzyme is not present in healthy cells Salvestrols exert no effects.

These plant derived molecules or nesem extracts provide a cell rescue mechanism and protection beyond antioxidant activities.

Changes in cropping and how food is grown commercially has resulted in lower levels of these key phytonutrients or nesems in our daily diet. Going organic is definitely helpful, trying to eat or choose foods which have been allowed to ripen on the plant/in season is another step forward.

Taking Salvestrol® daily in the morning on an empty stomach, at a varying dose to suit your needs is a great addition to a healthy diet and lifestyle, especially when its so hard to find seasonal organic foods that have ripened on the plant naturally.

Serving size 1 Vegetable Capsule (hydroxypropylmethylcellulose)

• Citrus Bioflavonoids (Citrus sinesis) - 300mg
• Grape seed (Vitis vinifera) - 75mg
• Pumpkin (Curcubita maxima) - 75mg
• Bulking agent (rice flour) - 50mg
• Total: 500mg

NO GRAPEFRUIT or extract from GRAPEFRUIT.

Contains extracts from Grape Seed but not grapes.

Directions

Recommended adult dose 

Take  recommended number of capsule(s), at least 30mins before food, in the morning on waking, as recommended by your health care practitioner. 

For best results we recommend the advice of a health care practitioner who can provide you with a personalised approach to dosing. Follow the instructions given to you by your qualified practitioner. If in doubt, please contact us to speak with our Clinical Support Team for advice – info@salvacare.co.nz or phone us on 09 476 9960 

Pre-cautions 

• Consult your health care professional prior to use if pregnant or breastfeeding.
• Colour may vary from batch to batch.
• No artificial flavours, colours or preservatives.
• Storage – store in a cool dry place below 25C.
• Keep out of reach from children.
• Dietary supplements should not be used as a substitute for a balanced diet and healthy lifestyle.

Salvestrol® is a registered trademark licensed to Nature’s Defence Research Ltd

1. Can I take Salvestrols with Chemotherapy or radiation? 

Salvestrols are plant-derived compounds; there are no reported side effects and no known interactions between Salvestrol and conventional treatments, including chemotherapy and radiotherapy.  A small study in an Indian population undergoing conventional treatment for Malignancies of the head, neck, GIT, ovary, Breast, lung showed Salvestrols may improve Quality of Life, overall survival when Salvestrols were used alongside conventional cancer treatments. 

Effect of NESEM™/S2013 in Indian Population undergoing Conventional Treatment for the Malignancies of the Head & Neck, GIT, Ovary, Breast and Lung as an Adjunct

2. Can I break open the capsules and take them as a powder? 

Yes, you can open the capsules and take them, they taste very bitter so try a small amount first to see if it is palatable to you. 

3. Can I take other supplements between my two doses? 

Taking a multivitamin and multi-mineral supplement can increase the effectiveness of Salvestrols. The specific cofactors are: Biotin, vitamin B3, vitamin B12, vitamin C, iron, and magnesium. These can be taken between the doses. 

4. I will be using CBD and THC oils, can I use Salvestrols as well? 

We suggest taking the Salvestrols in the morning and the THC/CBD as far away from the Salvestrols as possible. I.e. late afternoon/evening as we do know there may be overlap. 

5. Why do I have to take Salvestrol on an empty stomach? 

This is so the Salvestrols are not competing for absorption with other nutrients and give the Salvestrols the best chance of being fully utilized by the body. 

 

6. Why do I have to take two doses of Salvestrols instead of one? 

Salvestrols reach peak concentration after 3 hours after ingestion, the second dose boosts blood levels as the concentration of the 1st dose diminishes, allowing for peak levels to be reached in your body for a longer, lengthening the therapeutic window. 

7. Why do you say to go for a walk 4 hours after taking the second dose of Salvestrols? 

The Salvestrols will reach a peak concentration in your blood three hours after taking them and to provide an oxygen-rich environment for this metabolism, take some form of exercise around four hours after taking your Salvestrols. This can be as simple as a brisk walk around your neighbourhood. When taking exercise is not possible engage in breathing exercises for about 10 minutes. 

 

8. What do the 2000 points mean? 

In New Zealand, each capsule has “2000 points” which relates to the DNA-damaged cell selectivity of the proprietary blend of Salvestrols. No matter what fruit or vegetables are on the label, they will always make up the potency of 2000 active Salvestrols. Other countries like England and Europe have different amounts in their bottles, though ours are the highest. 

 

9. Why do you say to take 1000mg of Vitamin C with the Salvestrols? 

Ascorbic acid provides the electron donation that supports the metabolism of Salvestrol by CYP1B1. This allows it to keep circulating in your body longer, optimizing its effectiveness. 

 

10. If I forget to take them in the morning can I have them in the afternoon/evening? 

Although Salvestrols are metabolized in your body throughout the day, we recommend taking Salvestrols in the morning as this is when the CYP1B1 enzyme has the greatest activity. 

Tip: Put them beside your bedside table or in the bathroom to help you remember to take them or put an alarm on your phone. 

Naturally Elicited, Specifically Extracted Molecules (NESMs) are compounds that plants produce naturally as a protective mechanism during the ripening phase. These molecules are produced in response to environmental challenges, such as attacks by bacteria, viruses, or pathogens, especially in plants that are not treated with pesticides or modified. Using a targeted approach, NESMs are extracted through supercritical fluid extraction, which isolates specific molecules from their natural site of production, typically the plant's skin or pith.

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• Great Lakes Collagen
• Essential Fatty Acids

• Salvestrols–Natural Products with Tumour Selective Activity
• Regulation, Function, And Tissue-Specific Expression Of Cytochrome P450 Cyp1b1 
• Effect of NESEM™/S2013 in Indian Population undergoing Conventional Treatment for the Malignancies of the Head & Neck, GIT, Ovary, Breast and Lung as an Adjunct 
• Cancer and Related Case Studies Involving Salvestrol and CYP1B1 
• Nutrition and Cancer: Further CXase Studies Involving Salvestrol
• Salvestrols A natrual, targeted approach to preventing and treating cancer 
• Natural Cancer Therapy and Prevention Targeted on Cancer Cells and Cancer Stem Cells Based on the Cytochrome P45O Enzyme CYP1B1: A Commentary 
• Cytochrome P450 1B1 is overexpressed and regulated by hypomethylation in prostate cancer 
• Immunohistochemical evaluation of cytochrome P450 (CYP) and p53 in breast cancer

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The content is not intended to be a substitute for professional advice, diagnosis, or treatment. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website/blog/email.